Healthy Live
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Researchers develop optical biopsy system that detects liver cancer

Melody G. Gillette
Researchers develop optical biopsy system that detects liver cancer
Researchers developed a new optical biopsy system that is compatible with a needle biopsy system and can distinguish between cancerous and healthy liver tissue. Credit: Evgenii Zherebtsov, Orel State University

Researchers have developed an optical biopsy system that can distinguish between cancerous and healthy liver tissue. The new technology could make it easier to diagnose liver cancer, which is the sixth most common cancer globally.

“The instrument is designed to be compatible with the needles currently used for liver biopsies,” said Evgenii Zherebtsov, a member of the research team from Orel State University in Russia. “It could thus one day help surgeons more precisely navigate the biopsy instrument to decrease the number of errors in taking tissue samples that are used for diagnosis.”

In the Optica Publishing Group journal Biomedical Optics Express, the researchers report that the optical biopsy system can reliably distinguish between cancerous and healthy cells

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Medical Treatment
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Researchers develop injection to treat skin cancer

Melody G. Gillette
Yale researchers develop injection to treat skin cancer
Bioadhesive nanoparticles (white) after being taken up by skin cancer tumor cells during in virtro culture. Credit: Julia Lewis

Yale researchers are developing a skin cancer treatment that involves injecting nanoparticles into the tumor, killing cancer cells with a two-pronged approach, as a potential alternative to surgery.

The results are published in the Proceedings of the National Academy of Sciences.

“For a lot of patients, treating skin cancer is much more involved than it would be if there was a way to effectively treat them with a simple procedure like an injection,” said Dr. Michael Girardi, professor and vice chair of dermatology at Yale Medical School and senior author of the study. “That’s always been a holy grail in dermatology—to find a simpler way to treat skin cancers such as basal cell carcinoma and squamous cell carcinoma.”

For the treatment, tumors are injected with polymer-based nanoparticles carrying a chemotherapy

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