Yale researchers are developing a skin cancer treatment that involves injecting nanoparticles into the tumor, killing cancer cells with a two-pronged approach, as a potential alternative to surgery.
The results are published in the Proceedings of the National Academy of Sciences.
“For a lot of patients, treating skin cancer is much more involved than it would be if there was a way to effectively treat them with a simple procedure like an injection,” said Dr. Michael Girardi, professor and vice chair of dermatology at Yale Medical School and senior author of the study. “That’s always been a holy grail in dermatology—to find a simpler way to treat skin cancers such as basal cell carcinoma and squamous cell carcinoma.”
For the treatment, tumors are injected with polymer-based nanoparticles carrying a chemotherapy